Registered Nurses' Association of Ontario

Nursing Best Practice Guidelines

Signs and Symptoms of Venous Leg Ulcer Infection


  • Increased pain
  • New areas of wound breakdown
  • Friable granulation tissue
  • Foul odour
  • Increased exudate
  • Bright red granulation tissue
  • Bridging of soft tissue and epithelium
  • Erythema >2cm beyond the border of the wound
  • Increase in ulcer size


  • Fever
  • Rigors
  • Chills
  • Hypotension