Registered Nurses' Association of Ontario

Nursing Best Practice Guidelines

Drugs that can Cause Symptoms of Depression
Antihypertensives
  • Reserpine
  • Methyldopa
  • Propranolol
  • Clonidine
  • Hydralazine
  • Guanethidine
Antimicrobials
  • Sulfonamides
  • Isoniazid
Others
  • Cimetidine
  • Cancer chemotherapeutic agents
  • Alcohol
Analgesics
Narcotic
  • Morphine
  • Codeine
  • Meperidine
  • Pentazocine
  • Propoxyphene

Non-narcotics

  • Indomethacin
Cardiovascular Preparations
  • Digitalis
  • Diuretics
  • Lidocaine
Hypoglycemic Agents
 
Antiparkinsonism Drugs
  • Levodopa
Steroids
  • Corticosteroids
  • Estrogen
Psychotropic Agents
Sedatives
  • Barbiturates
  • Benzodiazepines
  • Meprobamate

Antipsychotics

  • Chlorpromazine
  • Haloperidol
  • Thiothixene

Hypnotics

  • Chloral hydrate
  • Benzodiazepines
  • Flurazepam

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Referemces:
Kane, R. L., Ouslander, J. G., & Abrass, I. B. (1999). Esssentials of clinical geriatrics. (4th ed.). New York: McGraw-Hill.

Levenson, A. J. & Hall, R. C. W. (1981). Neuropsychiatric manifestations of physical disease in the elderly. New York: Raven Press.

Piven M. L. S. (1998). Evidence-Based Protocol: Detection of depression in the cognitively intact older adult. In M. G. Titler (Series Ed.), Series on Evidence-Based Practice for Older Adults. Iowa City, IA: The University of Iowa College of Nursing Gerontological Nursing Interventions Research Center, Research Dissemination Core.

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