Registered Nurses' Association of Ontario

Nursing Best Practice Guidelines

Change Times According to Solution Type
Solution Type Set Change Frequency
Parenteral Nutrition (Amino Acids) q 72 hours or when integrity compromised
Lipids, Parenteral Nutrition Solutions containing Lipids q 24 hours or when integrity compromised
Whole blood & components (platelets, red blood cell concentrate, plasma, cryoprecipitate) 4 hours or 2 units or immediately upon suspected contamination
Fractionated products (IvIG, Clotting factors, Albumin) Upon completion of infusion